Epidemiol Rev 1997;19:175-180
© 1997 by the Johns Hopkins Bloomberg School of Public Health
FUTURE DEVELOPMENTS |
Genetic Epidemiology and the Future of Disease Prevention and Public Health
Task Force on Genetics in Disease Prevention, Centers for Disease Control and Prevention Atlanta, GA
Reprint requests to Dr. Muin J. Khoury, Task Force on Genetics in Disease Prevention, Centers for Disease Control and Prevention, Mailstop F45, 4770 Buford Highway, Atlanta GA 30341-3724
Received for publication December 10, 1996; accepted for publication May 19, 1997.
"As he chats with the young mother, the doctor flicks a cotton swab into the mouth of her infant son, collecting a small sample of mucus from inside his cheek. In the back room of his office, he inserts the sample into a machine, which extracts DNA from the mucus cells and compares it with the genetic material on a dime-size chip. Minutes later, a computer printer begins to spit out a list of the infant's genes. Fortunately, all but a few genes are labeled ‘normal.’ It is those few that the doctor discusses as he explains the results to the mother. ‘Your son's genetic inheritance is generally good’, he says ‘but he is somewhat predisposed to skin lesions. So starting right away, he should be protected against excessive exposure to the sun.’ And the doctor warns, ‘he may well be susceptible to cardiovascular disease later in life. To lessen this nsk, after about age 2, he should begin a lifelong low-fat high fiber diet’" (1, p. 24).
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